Equip \(\mathbf{Top}\) with the model structure in which a map \(f \colon X \to Y\) is:
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a weak equivalence if \(f_* \colon \pi_n(X, x_0) \to \pi_n(Y, f(x_0))\) is a bijection for all \(n\) and all \(x_0\text{;}\)
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a cofibration if it is the inclusion of a relative CW complex, or a retract of such a map;
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a fibration if it is a Serre fibration.
Cofibrant objects are retracts of CW complexes; cofibrant replacement is CW approximation (Theorem 9.17). Every object is fibrant. The homotopy category \(\mathrm{Ho}(\mathbf{Top})\) is the classical homotopy category, equivalent to the category of CW complexes and homotopy classes of maps.
